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Image Unavailable-76120-748

Anti-C1orf159 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. There are about 3000 genes on chromosome 1 and, considering the great number of genes, there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson?s, Gaucher?s disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf159 gene product has been provisionally designated C1orf159 pending further characterization.
Catalog Number: 76120-748
Supplier: Bioss
Image Unavailable-CA1.07531.0005

1-(2-Pyridylazo)-2-naphthol (PAN) indicator for metal titration, Supelco®

Description: Grade Reagent Ph Eur, Cas Number 85-85-8
Catalog Number: CA1.07531.0005
Supplier: MilliporeSigma

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Image Unavailable-CAPIPA526421

Anti-HBA2 Rabbit Polyclonal Antibody

Description: This antibody is predicted to react with non-human primate based on sequence homology. HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Catalog Number: CAPIPA526421
Supplier: Thermo Scientific
Product Image-59580-322

VWR® Solid Rubber Stoppers, Black

Description: These solid, black stoppers contain a high percentage of pure rubber, weigh less than neoprene, and are low in free sulfur (<sup>1</sup>/<sub>2</sub>%).
Catalog Number: 59580-322
Supplier: VWR International
Image Unavailable-TCC0385-010G

Copper PAN

Description: CAS Number: 23299-85-6
MDL Number: MFCD00067176
Form: Crystal
Color: Yellow Red
Catalog Number: TCC0385-010G
Supplier: TCI America

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Product Image-CAJT4320-7

Zinc chloride 97.0-100.5%, granular USP, J.T.Baker®

Description: Granular. GMP manufactured. Preserve in a tight container.
Catalog Number: CAJT4320-7
Supplier: AVANTOR PERFORMANCE MATERIAL LLC

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Image Unavailable-CAPIPA5-12745

Anti-FGFR1 Rabbit Polyclonal Antibody

Description: This antibody is predicted to react with chicken and mouse based on sequence homology. FGFR1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.
Catalog Number: CAPIPA5-12745
Supplier: Thermo Scientific
Image Unavailable-CAPIPA5-13117

Anti-EPR1 Rabbit Polyclonal Antibody

Description: Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.
Catalog Number: CAPIPA5-13117
Supplier: Thermo Scientific
Image Unavailable-TCA0009-5G

4-Acetamidobenzaldehyde ≥98.0%

Description: CAS Number: 122-85-0
MDL Number: MFCD00003380
Molecular Formula: C9H9NO2
Molecular Weight: 163.18
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 156
Catalog Number: TCA0009-5G
Supplier: TCI America

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Image Unavailable-TCD2721-005G

1,2,10-Decanetriol ≥97.0%

Description: CAS Number: 91717-85-0
MDL Number: MFCD00797600
Molecular Formula: C10H22O3
Molecular Weight: 190.28
Purity/Analysis Method: >97.0% (GC)
Form: Crystal
Melting point (°C): 66
Catalog Number: TCD2721-005G
Supplier: TCI America

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Image Unavailable-TCT1290-25G

Trifluoromethanesulfonamide ≥98.0% (by titrimetric analysis)

Description: CAS Number: 421-85-2
MDL Number: MFCD00068714
Molecular Formula: CH2F3NO2S
Molecular Weight: 149.09
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Color: White
Melting point (°C): 120
Catalog Number: TCT1290-25G
Supplier: TCI America

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Product Image-10750-356

Anti-JPH4 Rabbit Polyclonal Antibody

Description: JPH4 Antibody: Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain. In the CNS, both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons. Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions.
Catalog Number: 10750-356
Supplier: Prosci
Image Unavailable-76108-640

Anti-KLHDC9 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Kelch domain-containing protein 9 (KLHDC9), also designated Kelch/ankyrin repeat-containing cyclin A1-interacting protein (KARCA1), contains 3 Kelch repeats and interacts with CCNA1. The gene encoding KLHDC9 maps to chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Catalog Number: 76108-640
Supplier: Bioss
Image Unavailable-10482-678

Anti-KLHDC8A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Kelch domain-containing protein 8A (KLHDC8A) is a 350 amino acid protein. KLHDC8A contains seven kelch repeats, each of which is an approximately 50 amino acid long conserved region that forms a tertiary structure beta-propeller. The gene that encodes KLHDC8A is located on chromosome 1, which is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Catalog Number: 10482-678
Supplier: Bioss
Product Image-10750-352

Anti-JPH4 Rabbit Polyclonal Antibody

Description: JPH2 Antibody: Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain and contribute to the subsurface cistern formation in neurons. JPH2-null mice died of embryonic cardiac arrest and human patients with mutations in the JPH2 gene showed hypertrophic cardiomyopathy, demonstrating the importance of this protein. Multiple isoforms of JPH2 are known to exist.
Catalog Number: 10750-352
Supplier: Prosci
Image Unavailable-TCC1418-1G

(-)-trans-1,2-Cyclohexanedicarboxylic anhydride ≥98.0%

Description: CAS Number: 31982-85-1
MDL Number: MFCD00674195
Molecular Formula: C8H10O3
Molecular Weight: 154.17
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 166
Specific rotation [a]20/D: -85 deg (C=1, Dioxane)
Catalog Number: TCC1418-1G
Supplier: TCI America

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