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Catalog Number: (89418-792)
Supplier: Prosci
Description: Caspase-12 peptide is used for blocking the activity of the Caspase-12 antibody.


Catalog Number: (10749-410)
Supplier: Prosci
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta.


Catalog Number: (ABCA_AB34722-50UG)
Supplier: Abcam
Description: FITC Rat monoclonal [CD3-12] to CD3.

New Product


Catalog Number: (10483-954)
Supplier: Bioss
Description: Galectin-12, also designated galectin-related inhibitor of proliferation 1 in mouse, is a 314 amino acid protein encoded by the human gene LGALS12. Galectin-12 is a member of the galectin family consisting of b-galactoside-binding proteins with conserved carbohydrate recognition domains. Galectin-12 binds lactose and may participate in the apoptosis of adipocytes. This protein is preferentially expressed in peripheral blood leukocytes and adipocytes. Galectin-12 is induced by cell cycle block at the G1 phase and causes G1 arrest when overexpressed. The galectin-12 gene is expressed in mouse preadipo-cytes and is upregulated when preadipocytes undergo cell cycle arrest, concomitant with acquisition of the competence to undergo differentiation in response to adipogenic hormone stimulation. Galectin-12 is an adipocyte-expressed protein which is downregulated by various insulin resistance-inducing hormones. As a result, galectin-12 may play a role in the pathogenesis of insulin resistance.


Catalog Number: (SXS-1750)
Supplier: SPEX CERTIPREP LLC
Description: Single-Component organic standards.


Catalog Number: (SXS-1572)
Supplier: SPEX CERTIPREP LLC
Description: Single-Component organic standards.


Supplier: Buchi
Description: Evaporate up to 12 samples simultaneously by efficient vacuum vortex technology.

Catalog Number: (89054-504)
Supplier: Ace Glass
Description: 12 L Round Bottom Flask Reaction Stand Motor Mount for use with 89054-512.

Small Business Enterprise Product available on GSA Advantage®


Catalog Number: (10112-896)
Supplier: Prosci
Description: Polyclonal, Host: Goat, Species: Human, MouseImmunogen: TAIP-12 antibody was raised against a 15 amino acid synthetic peptide near the internal region of TAIP-12, Application: ELISA, WB


Catalog Number: (CA431601-BL)
Supplier: Biolegend
Description: Kit Contents
Mouse IL-12/IL-23 (p40) ELISA MAX™ Capture Antibody (200X)
Mouse IL-12/IL-23 (p40) ELISA MAX™ Detection Antibody (200X)
Mouse IL-12/IL-23 (p40) Standard
Avidin-HRP (1000X)


Supplier: VWR International
Description: For Library Tubes. 80 strips per pack. Polyethylene
Catalog Number: (ABCA_AB95528-100TE)
Supplier: Abcam
Description: PE Mouse monoclonal [HP-40] to IL-12.

New Product


Catalog Number: (103010-166)
Supplier: Anaspec Inc
Description: Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components


Supplier: Abcam
Description: Rabbit monoclonal [EPR9957(B)] to alpha 1,2 Mannosidase IA/MAN1A1 - BSA and Azide free.

New Product

Supplier: Portwest
Description: This stylish shirt is lightweight and comfortable. Maximum protection is guaranteed with permanent flame resistance and ARC2 protection against electric arc.

Catalog Number: (77440-786)
Supplier: Bioss
Description: IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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