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Product Image-97063-766

Guanidinium hydrochloride, Proteomics Grade

Catalog Number: (97063-766)
Supplier: VWR
Description: Guanidinium hydrochloride, Proteomics Grade

SDS Certificates


Product Image-10750-392

Anti-EBI3 Rabbit Polyclonal Antibody

Catalog Number: (10750-392)
Supplier: Prosci
Description: EBI3 Antibody: EBI3 is a subunit in two distinct heterodimeric cytokines: interleukin-27 (IL-27) and IL-35. Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naïve but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 (also known as TCCR) and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet. IL-35 is composed of EBI3 and the p35 subunit of IL-12 and has been reported to have therapeutic effects against collagen-induced arthritis by expanding the population of regulatory T cells and suppressing Th17 cells. At least two isoform of EBI3 are known to exist.
Product Image-CA11028-246

Combined Hematoxylin and Eosin/Methenamine Silver Stain for the Histological Diagnosis of Fungi in Tissue, Electron Microscopy Sciences

Catalog Number: (CA11028-246)
Supplier: Electron Microscopy Science
Description: A Combined Hematoxylin and Eosin/Methenamine Silver Stain is used for the Histological Diagnosis of Fungi in Tissue Sections.
Image Unavailable-75794-048

Human Recombinant IGFLR1 (from HEK293 cells)

Catalog Number: (75794-048)
Supplier: Prosci
Description: Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
Product Image-CAMK771604

Guanidinium hydrochloride ≥99.5%, GenAR® for biotechnology, Macron Fine Chemicals™

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Tested for absence of detectable aldehydes and ammeline. DNase-, RNase-, and protease-free.

Certificates

Product Image-CAMK0507F9

Guanidinium hydrochloride ≥99.5%, white powder, GenAR® for biotechnology, Macron Fine Chemicals™

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: White powder.

Certificates

Image Unavailable-10086-954

Anti-fetuin-B Rabbit Polyclonal Antibody

Catalog Number: (10086-954)
Supplier: Proteintech
Description: Fetuin-B is a protein that in humans is encoded by the FETUB gene. The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. It may be a protease inhibitor required for egg fertilization.
Product Image-10821-904

Human Recombinant Prolactin (from E. coli)

Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
Description: Prolactin is a hormone that is produced and secreted by the pituitary gland. Prolactin acts in an endocrine, paracrine, and autocrine manner. The prolactin receptor (PRLR) is expressed on many cell types, including cells of the reproductive organs, central nervous system, and breast cancer. Prolactin signal transduction occurs via JAK kinase signaling pathways. The primary function of prolactin is to regulate lactation, but prolactin also plays functional roles in the immune system and during cell growth, apoptosis, and differentiation.

Image Unavailable-CAAAJ61349-MA

Nigericin sodium salt ≥98%

Catalog Number: (CAAAJ61349-MA)
Supplier: Thermo Scientific Chemicals
Description: A potassium ionophore

Certificates


Product Image-CAMK050606

Guanidinium hydrochloride 99.5-101.0%, NF-GenAR® for biotechnology, Macron Fine Chemicals™

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Guanidinium hydrochloride 99.5-101.0%, GenAR* for biotechnology, Synonyms: Guanidinium chloride, Guanidine hydrochloride, Guanidine chloride, Guanadine hydrochloride, Packaging: Mall Polystormor Poly/Plastic Bottle, Size: 500g

Product Image-CAMK056326

Guanidinium hydrochloride solution 6 M, GenAR® for biotechnology, Macron Fine Chemicals™

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Clear, colorless liquid. Suitable for use in biotechnology. GMP manufactured product.

Product Image-10093-470

Anti-RCN2 Rabbit Polyclonal Antibody

Catalog Number: (10093-470)
Supplier: Proteintech
Description: Reticulocalbin 2 (RCN2) is a Ca(2+)-binding protein that is specifically localized in the endoplasmic reticulum (ER). It is also termed ERC-55, i.e. ER calcium-binding protein of 55 kDa. It is a single copy gene and is encoded by an approximately 1900-base mRNA, which shows a ubiquitous expression pattern. The protein comprises an amino-terminal signal sequence followed by six copies of the EF-hand Ca2+ binding motif.
Product Image-10750-552

Anti-SHOC2 Rabbit Polyclonal Antibody

Catalog Number: (10750-552)
Supplier: Prosci
Description: SHOC2 Antibody: SHOC2 protein participates in protein binding / transferase activity in the fibroblast growth factor receptor signaling pathway and Ras protein signal transduction. It is a widely expressed protein composed almost entirely of leucine-rich repeats (LRR), with a lysine-rich sequence at the amino terminus and cytoplasmically localized. SHOC2 acts as a positive modulator of the RAS-MAPK signaling cascade, which is elicited by EGL-15 and LET-23 and mediated by LET-60. SHOC2 together with protein phosphatase 1c (PP1c) forms a highly specific M-Ras effector complex and is essential for activation of the MAPK pathway by growth factors. Furthermore, in tumor cells with Ras gene mutations, inhibition of SHOC2 expression inhibits MAPK, but not PI3K activity. The SHOC2-PP1c holoenzyme provides an attractive therapeutic target for inhibition of the MAPK pathway in cancer. Recent studies show that aberrantly acquired N-myristoylation of SHOC2 causes human disease Noonan-like syndrome with loose anagen hair.
Product Image-10748-932

Anti-VCL Rabbit Polyclonal Antibody

Catalog Number: (10748-932)
Supplier: Prosci
Description: Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development. Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail. Expression of vinculin were shown to be affected by the level of actin expression. Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth. Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W).
Product Image-97061-256

TRIS HCl (tris(hydroxymethyl)aminomethane hydrochloride), Ultrapure

Supplier: VWR
Description: Reagent for stabilization of buffer formulations and electrophoresis of biological molecules.

SDS Certificates

Product Image-97062-038

Benzamidine hydrochloride hydrate ≥98% (by anhydrous basis), powder, Ultra Pure Grade

Catalog Number: (97062-038)
Supplier: VWR
Description: A protease inhibitor of arginine-selective enzymes like trypsin, kallikrein and thrombin.

SDS Certificates


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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