You Searched For: (1R)-Camphor+oxime

Catalog Number: (10749-636)

Supplier: Prosci

Description: SIGIRR Antibody: SIGIRR is a member of the Toll-like receptor-interleukin 1 receptor superfamily. Members of this family are defined by the presence of an intracellular Toll-IL-1R (TIR) domain. The Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SIGIRR was originally identified through database analysis and was shown to have only one Ig domain as opposed to the normal three Ig folds seen in the TIR family. Similar to ST2, another TIR family member, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor signaling. However, SIGIRR inhibits TLR-IL-1R signaling by dimerizing with TLR4, TLR5, TLR9, and IL-1R. It also associates with the down-stream TLR signaling proteins IRAK and TRAF6 in an IL-1-dependent fashion.

Supplier: Thermo Scientific Chemicals

Description: Fieser: 14,201 16,204

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Supplier: Enzo Life Sciences

Description: Immunosuppressant.

Supplier: TCI America

Description: CAS Number: 14073-97-3
MDL Number: MFCD00001634
Molecular Formula: C10H18O
Molecular Weight: 154.25
Purity/Analysis Method: >90.0% (GC)
Form: Clear Liquid
Boiling point (°C): 88
Flash Point (°C): 72
Specific Gravity (20/20): 0.89
Specific rotation [a]20/D: -19.5 deg (neat)

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Catalog Number: (76100-420)

Supplier: Bioss

Description: This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Supplier: Enzo Life Sciences

Description: GEF inhibitor

Catalog Number: (77977-495)

Supplier: LGC Standards

Description: TRC Amoxicillin Trihydrate

New Product

Supplier: TCI America

Description: Genipin, Purity: >97.0%(GC), CAS number: 6902-77-8, Molecular Formula: C11H14O5, MW: 226.23, Synonym: Methyl (1S,2R,6S)-2-Hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate, Physical state: Solid, Form: Crystal- Powder, Colour: White - Almost white, Size: 25MG

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Catalog Number: (10749-308)

Supplier: Prosci

Description: MYD88 Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires IL-1 receptor complex including IL-1RI and IL-1RAcP. Recently, MyD88 was identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment and dominant negative form of MyD88 attenuates IL-1R-mediated NF-kappa B activation. MyD88 is also employed as a regulator molecule by IL-18 receptor and human Toll receptor, which are members in the Toll/IL-1R family of receptors. Targeted disruption of the MyD88 gene results in lose of cellular responses to IL-1 and IL-18, and MyD88-deficient mice lack responses to bacterial product LPS that employs Toll-like receptors 2 and 4 (TLR2 and TLR4) as the signaling receptors. MyD88 is a general adapter protein for the Toll/IL-1R family of receptors and plays an important role in the inflammatory response induced by cytokines IL-1 and IL-18 and endotoxin. MyD88 gene is expressed in many tissues.

Catalog Number: (89415-326)

Supplier: Prosci

Description: IRAK-2 Antibody: The pro-inflammatory cytokine IL-1 induces cellular response through two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 receptor-associated kinase (IRAK) mediates activation of NF-kappa B, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK2. Both IRAK and IRAK2 recruit to the subunits of the IL-1R complex after IL-1 binding and lead to NF-kappa B activation. IRAKs also associate with Toll like receptor (TLR) and the dominant negative mutants of IRAKs inhibit LPS-induced NF-kappa B activation. Members in IRAK/Pelle family play a central role in IL-1R and TLR mediated inflammatory response. IRAK2 is expressed in a variety of human tissues.

Catalog Number: (TCA1107-025ML)

Supplier: TCI America

Description: CAS Number: 2623-23-6
MDL Number: MFCD00001482
Molecular Formula: C12H22O2
Molecular Weight: 198.31
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 228
Flash Point (°C): 98
Specific Gravity (20/20): 0.93
Specific rotation [a]20/D: -79.5 deg (neat)

SDS Certificates

Catalog Number: (89150-426)

Supplier: Enzo Life Sciences

Description: Antibiotic

Catalog Number: (89415-896)

Supplier: Prosci

Description: IRAK2 Antibody: The pro-inflammatory cytokine IL-1 induces cellular response through two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 receptor-associated kinase (IRAK) mediates activation of NF-kappa B, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family has been identified and designated IRAK2. Both IRAK and IRAK2 recruit to the subunits of the IL-1R complex after IL-1 binding and lead to NF-kappa B activation. IRAKs also associate with Toll like receptor (TLR) and the dominant negative mutants of IRAKs inhibit LPS-induced NF-kB activation. Members in IRAK/Pelle family play a central role in IL-1R and TLR mediated inflammatory response. Unlike human IRAK2, murine IRAK2 exists as four alternately spliced isoforms (IRAK2a-d), with two isoforms (IRAK2c and d) acting in an inhibitory fashion. IRAK2 is expressed in a variety of tissues.

Catalog Number: (89150-300)

Supplier: Enzo Life Sciences

Description: White to off-white crystalline powder

Supplier: Enzo Life Sciences

Description: Highly potent inhibitor of VEGFR-1 (IC50=130nM), VEGFR-2 (IC50=23nM) and VEGFR-3 (IC50=18nM). At higher concentrations it inhibits PDGFR-β (640nM), c-Kit (236nM) and CSF-1R (380nM).

Supplier: TCI America

Description: (stabilized with MEHQ)
CAS Number: 7534-94-3
MDL Number: MFCD00081070
Molecular Formula: C14H22O2
Molecular Weight: 222.33
Purity/Analysis Method: >85.0% (GC)
Form: Clear Liquid
Boiling point (°C): 129
Flash Point (°C): 144
Specific Gravity (20/20): 0.98

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