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Description: PPIF, also named as CYP3, PPIase F and Rotamase F, belongs to the cyclophilin-type PPIase family. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIF is a mitochondrial matrix protein involved in the induction of necrotic and apoptotic cell death through the activation of the mitochondrial permeability transition (mPT) pore. This antibody is immunized with full length gene PPIF and absorbed by PPIA. So this antibody is special to PPIF
Catalog Number: 10092-646
Supplier: Proteintech


Description: Sequence: Fmoc-γ-carboxy-Glu(OtBu)₂-OH
Catalog Number: B-1265.0250BA
Supplier: Bachem Americas


Description: The large molecular-weight immunophilin, FKBP52, is a known target of the immunosuppressive drug FK506. FKBP52 exhibits peptidyl-prolyl cis–trans isomerase (PPIase) activity, which is inhibited by the binding of FK506—properties that it shares with the smaller but better-studied immunophilin, FKBP12. It is essential to AR-mediated induction of genes involved in sexually dimorphic development of the penis (NKX3-1), in erectile function of the mature organ (NOS2 and NOS3), and in promotion of apoptosis during development.
Catalog Number: 10087-038
Supplier: Proteintech


Description: Sequence: Boc-Thr-OH
Catalog Number: A-2305.0100BA
Supplier: Bachem Americas


Description: N-Boc-L-alanine ≥98%
Catalog Number: CAAAA16018-14
Supplier: Thermo Scientific Chemicals

Description: Sequence: Fmoc-Lys(Boc)-OH
Catalog Number: B-1080.0025BA
Supplier: Bachem Americas


Description: A caspase inhibitor designed to facilitate cell permeability
Catalog Number: CAAAJ65812-LB0
Supplier: Thermo Scientific Chemicals

Description: Sequence: Fmoc-D-Asp-OtBu
Catalog Number: B-2305.0005BA
Supplier: Bachem Americas


Description: N-(tert-Butoxycarbonyl)-D-2-cyclohexylglycine, Purity: >98.0%(HPLC)(T), Cas no. 70491-05-3, Molecular formula: C13H23NO4, Form: Crystal- Powder, Colour: White - Almost white, Synonyms: Boc-D-Chg-OH, N-Boc-D-2-cyclohexylglycine, Size: 1G
Catalog Number: TCB4975-5G
Supplier: TCI America

SDS


Catalog Number: CAAAH59838-03
Supplier: Thermo Scientific Chemicals

Description: Sequence: H-Orn(Boc)-OH
Catalog Number: E-1625.0025BA
Supplier: Bachem Americas


Description: Sequence: Boc-Ala-OH
Catalog Number: A-1060.1000BA
Supplier: Bachem Americas


Description: CAS Number: 87120-72-7
MDL Number: MFCD01076201
Molecular Formula: C10H20N2O2
Molecular Weight: 200.28
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Melting point (°C): 45
Catalog Number: TCA2045-5G
Supplier: TCI America

Description: Sequence: Ac-Ser(tBu)-OH
Catalog Number: E-3010.0001BA
Supplier: Bachem Americas


Description: Sequence: Z-Asp(OtBu)-OH
Catalog Number: C-1355.0100BA
Supplier: Bachem Americas


Description: Human soluble DLL-1 comprises the extracellular signaling domain of DLL-1, a member of the Delta/Serrate/Lag-2 (DSL) family of single-pass type I trans-membrane proteins that serve as ligands for Notch receptors. It is expressed primarily in the heart, pancreas and epidermis. DLL-1 functions to specifically activate the Notch-1 and Notch-2 receptors. Proteolytic cleavage of DLL-1 produces a secreted extracellular domain, sDLL-1, that interacts with Notch receptors expressed on adjacent cells. Notch signaling plays an essential role in controlling cell fate decisions during prenatal development and postnatal stem cell renewal, and differentiation in many tissues. Human sDLL-1 blocks monocyte differentiation into macrophages, but permits differentiation into dendritic cells. In hematopoietic progenitor cells, hsDLL-1, suppresses differentiation into B-cells, while promoting differentiation into T-cells and NK cell precursors. In cell culture, human sDLL-1 has been shown to promote expansion of hematopoietic progenitor cells and suppress apoptosis by inhibiting differentiation. Overexpression of Notch receptors appears to inhibit differentiation in several mammalian cell lines, and increasing evidence suggests that Notch signaling is frequently downregulated in human malignancies. The human DLL-1 gene consists of a 528 amino acid extracellular domain with one DSL domain, eight EGF-like repeats, a 23 amino acid transmembrane domain, and a 155 amino acid cytoplasmic domain. The calculated molecular weight of Recombinant Human sDLL-1 is 56.3 kDa.
Catalog Number: 10779-414
Supplier: Peprotech


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