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Product Image-10100-184

Anti-DPPA2 Rabbit Polyclonal Antibody

Description: DPPA2 may play a role in maintaining cell pluripotentiality. ECSA/DPPA2 is a promising target for antigen-specific immunotherapy in non-small cell lung cancers.
Catalog Number: 10100-184
Supplier: Prosci
Image Unavailable-10340-900

Anti-KLK10 Rabbit Polyclonal Antibody (Cy5.5®)

Description: Has a tumor-suppressor role for NES1 in breast and prostate cancer.
Catalog Number: 10340-900
Supplier: Bioss
Image Unavailable-76119-330

Anti-Limd1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing 3 LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks <i>in vitro</i> and <i>in vivo</i> tumor growth and is down-regulated in lung cancer. Limd1 may regulate osteoclast development under stressful conditions via its interactions with TRAF6 and p62.
Catalog Number: 76119-330
Supplier: Bioss
Product Image-10751-722

Anti-SCUBE3 Rabbit Polyclonal Antibody

Description: SCUBE3 Antibody: SCUBE3 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and is highly expressed in primary osteoblasts and bones, and to a lesser extent in heart. Other studies have shown that overexpression of SCUBE3 in mice induced cardiac hypertrophy, suggesting that it may also play a role in the regulation of cardiac growth.. SCUBE3 has been shown to be an endogenous TGF-beta ; receptor ligand and is thought to promote lung cancer cell mobility and invasiveness. In lung cancer cells, the secreted SCUBE3 protein was cleaved by MMP2 and MMP9, allowing the activation of the TGF-beta ; receptor, the increase of Smad2/3 transcriptional activity and the upregulation of expression of proteins such as TGF-beta ;1, VEGF, Snail, and Slug.
Catalog Number: 10751-722
Supplier: Prosci
Product Image-10017-922

KIMBLE® KIMAX® Pink Colorware Erlenmeyer Flasks, DWK Life Sciences

Description: Please join us to support breast cancer prevention, treatment, and research by purchasing Pink Colorware from DWK Life Sciences.
Catalog Number: 10017-922
Supplier: DWK Life Sciences (KIMBLE)
Image Unavailable-10486-778

Anti-NHLRC3 Rabbit Polyclonal Antibody (Cy5®)

Description: NHLRC3 contains 4 NHL repeats. The function of the NHLRC3 protein remains unknown. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Catalog Number: 10486-778
Supplier: Bioss
Image Unavailable-CA90001-742

Diagnostic Tests—Adjuvant Complete to Neisseria meningitidis Antiserum, BD Diagnostics

Description: Antigens and antisera used for slide agglutination tests and immunofluorescence. BD Difco Listeria O Antigens Types 1 and 4 (Slide) are suspensions of appropriate<i> </i>serotypes containing 0.3% formaldehyde as a preservative
Catalog Number: CA90001-742
Supplier: BD

SDS Certificates


Image Unavailable-75953-256

Anti-HSPB1 Mouse Monoclonal Antibody (Biotin) [clone: HSPB1/774]

Description: This antibody recognizes a 24-27 kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27). Hsp27 was recently found to be identical to the estrogen-induced p29 and 24K protein. About 50% of breast carcinomas are positive for hsp27 especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells.
Catalog Number: 75953-256
Supplier: Biotium
Product Image-10093-652

Anti-RHOC Rabbit Polyclonal Antibody

Description: Ras homolog family member C (RHOC) encodes a Rho-related GTP-binding protein, which belongs to small GTPase superfamily and also Rho family. RHOC. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Expression of RHOC contributes to metastatic phenotype of melanoma cells and is associated with multiple cancers including gastric carcinomas, ovarian carcinomas and breast cancer as well.
Catalog Number: 10093-652
Supplier: Proteintech
Product Image-470315-658

ADC® Diagnostix 5110N Pocket Diagnostic Sets

Description: A pocket sized set with a protective hard case.
Catalog Number: 470315-658
Supplier: AMERICAN DIAGNOSTIC CORP CP
Image Unavailable-76107-222

Anti-CT74 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: CCDC36 , also known as CT74 (cancer/testis antigen 74), is a 584 amino acid protein that contains coiled-coil domains and is expressed as three alternatively spliced isoforms. The gene encoding CCDC36 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Catalog Number: 76107-222
Supplier: Bioss
Image Unavailable-76119-032

Anti-CCDC37 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: CCDC37 is a 611 amino acid protein that exists as two alternatively spliced isoforms. The gene encoding CCDC37 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Catalog Number: 76119-032
Supplier: Bioss
Image Unavailable-75977-824

Anti-TRIM29 Mouse Monoclonal Antibody [clone: TRIM29/1042]

Description: This antibody recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
Catalog Number: 75977-824
Supplier: Biotium
Product Image-10748-578

Anti-IL23A Rabbit Polyclonal Antibody

Description: IL-23 Antibody: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
Catalog Number: 10748-578
Supplier: Prosci
Image Unavailable-76110-788

Anti-AKD1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: AKD1 is a 1911 amino acid coiled-coil protein belonging to the adenylate kinase family. AKD1 exists as six alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 6q21. Chromosome 6 makes up nearly 6% of the human genome and contains 170 million base pairs, which encode 1200 genes. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. A bipolar disorder susceptibility locus is also linked to the q arm of chromosome 6. The PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatibility complex proteins are located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6.
Catalog Number: 76110-788
Supplier: Bioss
Image Unavailable-76120-860

Anti-C3orf39 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: C3orf39, also known as AGO61, is a 580 amino acid secreted protein belonging to the glycosyltransferase 61 family. C3orf39 is encoded by a gene that maps to human chromosome 3p25.1. Chromosome 3 is made up of approximately 214 million bases encoding over 1100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
Catalog Number: 76120-860
Supplier: Bioss
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