Human Recombinant CCL4 (MIP-1B) (from E. coli)
Supplier: CHEMOTACTICS, INC MS
Recombinant Human CCL4 (MIP-1B) in lyopholized format with very low endotoxin levels.
- Extremely low endotoxin levels (<0.01 EU per 1 μg)
- Functional activity tested and validated
- For use in various streptavidin applications: Flow cytometry, microscopy, and other imaging techniques
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
Ordering information: Larger sizes available, please request a custom quote.
Delivery information: Shipped lyophilized at room temperature.
Caution: For research use only, not for use in humans.
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