Human Recombinant Myostatin (from E. coli)

Supplier: VWR International

VWR100-22-100UG VWR100-22-10UG VWR100-22-1MG VWR100-22-500UG

77751-172EA 1464.15 CAD

77751-172 77751-174 77751-176 77751-186

Human Recombinant Myostatin (from E. coli)

Proteins and Peptides

Myostatin, also known as GDF-8, is a conserved member of the TGF-beta superfamily. Myostatin is an essential regulator of skeletal muscle mass and cardiac muscle development and function. Myostatin is a secreted protein that negatively regulates skeletal muscle growth by determining muscle fiber number and size. Myostatin binds one of the two activin type II receptors (ACTRIIA or ACTRIIB) to activate SMAD signaling. Myostatin also activates MAPK signaling through TAK1-MKK6 and Ras pathways. Inhibition of myostatin increases muscle mass in a number of human disease animal models, such as muscular dystrophy.

High quality
Low endotoxin
Affordable

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For research use only.

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