Human Recombinant IL-15 (from E. coli cells)

Supplier: VWR International

Human Recombinant IL-15 (from E. coli cells)

Human Recombinant IL-15 (from E. coli cells)

77753-380 77753-382 77753-384

77753-380EA 2908.35 CAD

77753-380 77753-382 77753-384

Human Recombinant IL-15 (from E. coli cells)

Proteins and Peptides

IL-15 is a widely expressed proinflammatory cytokine that is structurally and functionally related to IL-2. Signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. Regulates the activation of T cells, neutrophils, and macrophages, and is a stimulatory cytokine promoting dendritic cell function.

High quality
Low endotoxin
Lot-to-lot consistency
Animal free
Manufactured following GMP guidelines

Dysregulated in chronic inflammatory disorders, including rheumatoid arthritis, psoriasis, and pulmonary inflammatory diseases. Combines with other common γ chain cytokines (IL-2, IL-7 and IL-21) to promote favorable anti-tumoral phenotypes in adoptive cellular therapies such as CAR-T cell therapy. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.

Host cell protein: ≤30 ng/ml, host cell DNA: ≤0.01 ng/ml, sterility testing: No growth, mycoplasma: Negative

Caution:

For research use or further manufacturing only.

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