Human Recombinant R-SPONDIN-1 (from CHO cells)

Supplier: VWR International

Human Recombinant R-SPONDIN-1 (from CHO cells)

Human Recombinant R-SPONDIN-1 (from CHO cells)

77751-070 77751-072 77751-074 77751-076 77751-078

77751-070EA 1212.81 CAD

77751-070 77751-072 77751-074 77751-076 77751-078

Human Recombinant R-SPONDIN-1 (from CHO cells)

Proteins and Peptides

R-Spondin-1 (RSPO-1) is a secreted growth factor that stabilizes β-catenin and enhances WNT signaling. RSPO-1 is expressed in many tissues and regulates female sex determination, XX gonad development, oocyte differentiation, and hematopoietic stem cell specification. The RSPO-1 stabilization of β-catenin promotes intestinal crypt cell proliferation. This suggests that RSPO-1 functions as a stem cell growth factor and may have therapeutic potential in the treatment of gastrointestinal diseases and chemotherapy-induced intestinal mucositis. Additionally, recombinant RSPO-1 protein is used to initiate and maintain intestinal organoid cultures.

High quality
Low endotoxin
Affordable

Caution: For research use only.

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