tri-Sodium citrate dihydrate ≥99.0%, crystals, EMPROVE® ESSENTIAL Ph. Eur., BP, JP, USP, E331, SAFC®

Supplier: EMD MILLIPORE – PCS CA EXCEP

Synonyms: Sodium Citrate, DihydrateCitric acid trisodium salt dihydrateSodium Citrate DihydrateSodium citrate tribasic dihydrateSodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate

1.06432.5000 1.06432.9029 1.06432.9029
CA1.06432.9029EA 1041.3 CAD
CA1.06432.9029 EM1.06432.9029 CA1.06432.5000
tri-Sodium citrate dihydrate ≥99.0%, crystals, EMPROVE® ESSENTIAL Ph. Eur., BP, JP, USP, E331, SAFC®
tri-Sodium citrate dihydrate

Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).


Certifications: Corresponds to Ph. Eur., BP, JP, USP, E 331
Conforms to the purity criteria on food additives according to the current European Commission Regulation.

Formula: Na₃C₆H₅O₇·2H₂O
MW: 294.1 g/mol
Melting Pt: 150 °C (anhydr.)
MDL Number: MFCD00150031
CAS Number: 6132-04-3
Merck Index: 13,08675
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Specification Test Results

Assay (Perchloric acid titration, calc. on anhydrous substance (Ph Eur)) 99.0 - 101.0 %
Assay (Perchloric acid titration, previously dried substance) (JP/USP) 99.0 - 100.5 %
Identity (Na) passes test
Identity (Citrate) passes test
Identity (reaction upon ignition) passes test
Appearance white to almost white crystals
Appearance of solution (100 g/l, CO₂-free water) clear and colorless
Acidity or alkalinity passes test
pH (50 g/l CO₂-free water) 7.5 - 8.5
Chloride (Cl) ≤ 50 ppm
Sulfate (SO₄) ≤ 150 ppm
Heavy metals (as Pb) ≤ 5 ppm
Al (Aluminium) ≤ 5 ppm
As (Arsenic) ≤ 1 ppm
Hg (Mercury) ≤ 1 ppm
Pb (Lead) ≤ 1 ppm
Oxalate (as C₂H₂O₄) ≤ 100 ppm
Tartrate (C₄H₄O₆) passes test
Residual solvents (ICH (Q3C)) excluded by manufacturing process
Readily carbonisable substance passes test
Water (according to Karl Fischer) 11.0 - 13.0 %
Loss on drying (180 °C, 18 h) 10.0 - 13.0 %

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