L(+)-Histidine monohydrochloride monohydrate, Multi-Compendial, J.T.Baker®

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Synonyms: L-Histidine monohydrochloride monohydrate, (2S)-(+)-Histidine monohydrochloride monohydrate, L-Histidine hydrochloride monohydrate, (S)-(+)-Histidine monohydrochloride monohydrate, His HCl monohydrate, H-His-OH.HCl.H2O, H-His-OH·HCl·H₂O, L-3-Imidazol-4-ylalanine monohydrochloride monohydrate, L-Histidine hydrochloride hydrate

Management of Change (MOC) category = R

BAKR2081-06 BAKR2081-07
CAJT2081-6EA 1483.48 CAD
CAJT2081-6 CAJT2081-7 CAJT2081-9
L(+)-Histidine monohydrochloride monohydrate, Multi-Compendial, J.T.Baker®
L(+)-Histidine monohydrochloride monohydrate

Crystals or Crystalline Powder.

Formula: C₆H₉N₃O₂·HCl·H₂O
MW: 209.63 g/mol
Melting Pt: 259 °C
Density: 1.485 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00151027
CAS Number: 5934-29-2
EINECS: 211-438-9
Merck Index: 13,04741
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Specification Test Results

Meets B.P. Chemical Specifications
Meets E.P. Chemical Specifications
GMP Manufactured Product
Meets J.P. Chemical Specifications
Store in airtight container.
CAUTION: For Manufacturing, processing or repackaging
Bulk Pharmaceutical Chemical
EP/BP - Assay (C₆H₉N₃O₂·HCl) (dried basis) 98.5 - 101.0 %
EP/BP - Identification A Passes Test
EP/BP - Identification B Passes Test
EP/BP - Identification C Passes Test
EP/BP - Identification F Passes Test
EP/BP - Appearance of Solution Passes Test
EP/BP - pH 3.0 - 5.0
EP/BP - Specific Rotation [Å]²º^D (+) 9.2 - 10.6 Degree
EP/BP-Ninhydrin-Positive Substances-Each ≤0.2 %
EP/BP-Ninhydrin-Positive Substances-Total Impurities ≤0.5 %
EP/BP - Sulfate (SO₄) ≤300 ppm
EP/BP - Ammonium (NH₄) ≤0.02 %
EP/BP - Iron (Fe) ≤10 ppm
EP/BP - Loss on Drying at 150°C 7.0 - 10.0 %
EP/BP - Ash (sulfated) ≤0.1 %
JP - Identification Passes Test
JP - Optical Rotation (+) 9.2 - 10.6
JP - pH 3.5 - 4.5
JP - Clarity and Color of Solution Passes Test
JP - Sulfate (SO₄) ≤0.028 %
JP - Ammonium (NH₄) ≤0.02 %
JP - Heavy Metals (as Pb) ≤10 ppm
JP - Iron (Fe) ≤10 ppm
JP - Related Substances Passes Test
JP - Water 7.2 - 10.0 %
JP - Residue on Ignition ≤0.10 %
JP - Assay (anhydrous basis) 99.0 - 101.0 %
Endotoxin Concentration, IU/mg ,For Information Only
No Class 1,2,3 or other solvents are used or produced in the
manufacturing or purification of the product.
Elemental Impurities (USP 232, EP 5.20) - Information on elemental
impurities for this product is available on the associated Product
Regulatory Data Sheet and elemental impurity profile report.

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