Human Recombinant rh GM-CSF (GMP) (from E. coli)
Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
CTGrade GMP rh GM-CSF is a recombinant human protein that is produced from E. coli and is designed to support preclinical and clinical research, as well as commercial applications.
- High biological activity verified by a relevant bioactivity assay
- Low endotoxin levels
- ≥98% purity
- High lot-to-lot consistency
GM-CSF is a hematopoietic growth factor with the ability to form colonies of granulocytes and macrophages. Enhances the number of circulating white blood cells and function of neutrophils and monocytes. Regulates multiple functions via transcription factors in the differentiated cells, including cell survival, proliferation, and maturation. Generates in vitro murine and human DC populations from bone marrow precursors and blood monocytes, respectively. Human and mouse GM-CSF do not show cross-reactivity.
The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.
The CTGrade GMP products are manufactured in a facility that does not use or process beta-lactam containing materials. No animal- or human-derived materials were used during manufacturing or as ingredients.
Shelf life: Unopened vials are stable for 36 months from the date of manufacture as indicated on the label. Reconstituted material should be apportioned in working volumes and stored at or below −20°C in manual defrost freezer. For short term storage reconstituted material is stable for 4 to 6 weeks when stored at 2 to 8 °C. Stability can be increased by adding at least 0.1% carrier protein.
Certifications: These products are manufactured, tested, and released in an ISO 9001:2015 certified facility following cGMP practices.
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