Human Recombinant IL-15 (CTGrade GMP) (from E. coli)

Supplier: FUJIFILM IRVINE SCIENTIFIC, INC

500-08-100UG 500-08-1MG 500-08-50UG
77660-986EA 2281.61 CAD
77660-986 77660-988 77660-990
Human Recombinant IL-15 (CTGrade GMP) (from E. coli)
Proteins and Peptides

IL-15 is a widely expressed proinflammatory cytokine that is structurally and functionally related to IL-2.


  • High quality
  • Low endotoxin
  • Lot-to-lot consistency
  • Animal free
  • Manufactured following GMP guidelines


Signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors
Regulates the activation of T cells, neutrophils, and macrophages, and is a stimulatory cytokine promoting dendritic cell function
Dysregulated in chronic inflammatory disorders, including rheumatoid arthritis, psoriasis, and pulmonary inflammatory diseases
Combines with other common γ chain cytokines (IL-2, IL-7 and IL-21) to promote favorable anti-tumoral phenotypes in adoptive cellular therapies such as CAR-T cell therapy
The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance


Host Cell Protein: ≤30 ng/ml
Host Cell DNA: ≤0.01 ng/ml
Sterility testing: No Growth
Mycoplasma: Negative


Caution: For research use or further manufacturing only.

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SPECIFICATIONS

Protein/peptide name CTGrade GMP IL-15
Environmentally Preferable
Protein synonyms IL-T
Protein/peptide type Recombinant
Protein Function Cytokine
Species Human
Source E. coli
Conjugation Unconjugated
Gene ID P40933
Sequence MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS
Protease-free N
Animal-free Y
Nuclease-free N
Carrier-free Y
Endotoxin-free N
Endotoxin level Low
Endotoxin content Endotoxin LAL (EU/µg) ≤0.05
Accession no. P40933
Biological activity Bioactivity Assay: Proliferation of CTLL-2, ED₅₀ ≤1 ng/ml, Bioactivity ≥ 2x10⁴ IU/µg 
Purity ≥97%
Grade GMP
Formulation 10 mM Sodium bicarbonate, pH 8.5
Molecular weight 12.9 kDa
Reconstitution instructions Sterile water at 0.1 - 0.5 mg/ml
Storage conditions At or below –20 °C
Shipping temperature Ambient
Tested applications Bioassay

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