Rapamycin ≥99% (by HPLC), Sigma-Aldrich®

Supplier: MilliporeSigma

553210-100UG 553210-1MG
CA80054-244EA 178.27 CAD
CA80054-244 CA80054-246
Rapamycin ≥99% (by HPLC), Sigma-Aldrich®
Rapamycin

Antifungal and immunosuppressant


  • Clear film


Selectively inhibits the phosphorylation and activation of p70 S6 kinase (IC50=50pM). Prevents the translational activation of IGF-II. Shown to inhibit later signaling events such as p110Rb phosphorylation, p34cdc2 kinase activation and cyclin A synthesis. Exhibits strong binding to FK-506 binding proteins. Reported to induce apoptosis in a murine B cell line, to inhibit lymphokine-induced cell proliferation at the G1 phase and to irreversibly arrest Saccharomyces cerevisiae cells in the G1 phase.


Soluble in DMSO or MeOH

Formula: C₅₁H₇₉NO₁₃
MDL Number: MFCD00867594
CAS Number: 53123-88-9

Order Now


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR