Peroxynitrite

Supplier: EMD Millipore
516620-1SET 516620-1SET
CA80055-374EA 505.75 CAD
CA80055-374 80055-374
Peroxynitrite
Enzymes
Synthesized from isoamyl nitrite and hydrogen peroxide

Peroxynitrite (ONOO-) is a cell-permeable strong biological oxidizing agent that reacts with DNA, membrane phospholipids, sulfhydryl groups, and tyrosine. Has been implicated in a variety of pathophysiological conditions including acute respiratory distress syndrome (ARDS), arthritis, atherosclerosis, inflammatory bowel disease, ischemia-reperfusion, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity, and septic shock. Supplied with an informational insert.
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