Nα-(p-Toluenesulfonyl)-DL-lysine chloromethyl ketone hydrochloride, Calbiochem®

Supplier: MilliporeSigma

Synonyms: Nα-p-Tosyl-DL-lysine chloromethyl ketone hydrochloride, TLCK, Nalpha-p-Tosyl-DL-lysine chloromethyl ketone hydrochloride

616382-250MG 616382-50MG

CA80057-626EA 1015.52 CAD

CA80057-626 CA80057-628

Nα-(p-Toluenesulfonyl)-DL-lysine chloromethyl ketone hydrochloride, Calbiochem®

Nalpha-(p-Toluenesulfonyl)-DL-lysine chloromethyl ketone hydrochloride

Inhibits trypsin-like serine proteinases

Inactivates trypsin irreversibly without affecting chymotrypsin. Prevents nitric oxide production by activated macrophages by interfering with transcription of the iNOS gene. Blocks cell-cell adhesion and binding of HIV-1 virus to target cells. In macrophages, blocks nitric oxide synthase induced by interferon-[gamma] and lipopolysaccharides (EC50=80µM). Prevents endonucleolysis accompanying apoptotic cell death of HL-60 leukemia cells and normal thymocytes.

Formula: C₁₄H₂₂Cl₂N₂O₃S
MW: 369.31 g/mol

MDL Number: MFCD00012513
CAS Number: 4238-41-9

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