Phorbol-12-myristate-13-acetate, Sigma-Aldrich®

Supplier: MilliporeSigma

524400-10MG 524400-1MG 524400-25MG 524400-5MG
CA80055-398EA 1153.02 CAD
CA80055-398 CA80055-400 CA80055-402 CA80055-404
Phorbol-12-myristate-13-acetate, Sigma-Aldrich®
Phorbol-12-myristate-13-acetate

Most commonly-used phorbol ester


Extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro, even at nM concentrations. Promotes the expression of inducible NOS in cultured hepatocytes. Activates Ca2+-ATPase and potentiates forskolin-induced cAMP formation. Inhibits apoptosis induced by the FAS antigen, but induces apoptosis in HL-60 promyelocytic leukemia cells. Its binding is reversible.

Formula: C₃₆H₅₆O₈
MDL Number: MFCD00036736
CAS Number: 16561-29-8

Order Now


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR