Tris(hydroxymethyl)aminomethane (TRIS, Trometamol) 99.0-101.0% USP, Multi-Compendial, J.T.Baker®
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Synonyms:
Trizma(R) base
, TRIS base
, THAM
, 2-Amino-2-(hydroxymethyl)-1,3-propanediol
, Tris(hydroxymethyl)methylamine
, 2-Amino-2-(hydroxymethyl)propane-1,3-diol
, 2-Amino-2-(hydroxymethyl)propane-1,3-diol(tris)
, Tromethamine
Management of Change (MOC) category = R
J.T. Baker®
4102-06
4102-F8
4102-01
4102-F7
4102-05
BAKR4102-SD
BAKR4102-05
BAKR4102-F9
4102-07
BAKR4102-F7
4102-09
BAKR4102-07
BAKR4102-F8
4102-SD
BAKR4102-09
4102-F9
BAKR4102-01
BAKR4102-06
CAJT4102-06EA
19801.79
CAD
JT4102-06
CAJT4102-06
JT4102-1
CAJT4102-1
CAJT4102-5
CAJT4102-F8
CAJT4102-7
CAJT4102-F9
JT4102-9
CAJT4102-9
JT4102-7
JT4102-5
JT4102-SD
JT4102-F7
JT4102-F8
CAJT4102-F7
JT4102-F9
CAJT4102-SD
Tris(hydroxymethyl)aminomethane (TRIS, Trometamol) 99.0-101.0% USP, Multi-Compendial, J.T.Baker®
Tris(hydroxymethyl)aminomethane (TRIS, Trometamol)
Formula:
NH₂C(CH₂OH)₃ MW: 121.14 g/mol Boiling Pt: 357 °C (1013 hPa) Melting Pt: 169…172 °C Density: 1.328 g/cm³ (20 °C) |
MDL Number:
MFCD00004679 CAS Number: 77-86-1 Merck Index: 13,09842 |
Specification Test Results
Meets JPC (1997) Chemical Specifications | |
Meets B.P. Chemical Specifications | |
Meets E.P. Chemical Specifications | |
Meets U.S.P Requirements | |
GMP Manufactured Product | |
CAUTION: For Manufacturing, processing or repackaging | |
Bulk Pharmaceutical Chemical | |
USP - Assay (C₄H₁₁NO₃) | 99.0 - 101.0 % |
USP - Identification A | Passes Test |
USP - Identification B | Passes Test |
USP - Identification C | Passes Test |
USP - pH (1 in 20) | 10.0 - 11.5 |
USP - Loss on Drying | ≤1.0 % |
USP - Residue on Ignition | ≤0.1 % |
USP - Melting Range(Lower) | 168 - 172 °C |
USP - Melting Range(Upper) | 168 - 172 °C |
EP/BP - Assay (C₄H₁₁NO₃) (dried basis) | 99.0 - 100.5 % |
EP/BP - Identification B (melting point) | 168 - 174 °C |
EP/BP - Identification C | Passes Test |
EP/BP - Appearance of Solution | Passes Test |
EP/BP - pH | 10.0 - 11.5 |
EP/BP - Related Substances | ≤1.0 % |
EP/BP - Chloride (Cl) | ≤100 ppm |
EP/BP - Iron (Fe) | ≤10 ppm |
EP/BP - Loss on Drying at 105°C | ≤0.5 % |
EP/BP - Ash (sulfated) | ≤0.1 % |
JPC 1997 - Assay (C₄H₁₁NO₃) (dried basis) | ≥99.0 % |
JPC 1997 - Identification A | Passes Test |
JPC 1997 - Identification B | Passes Test |
JPC 1997 - pH | 10.3 - 10.7 |
JPC 1997 - Melting Point | 168 - 172 °C |
JP - Clarity and Color of Solution | Passes Test |
JPC 1997 - Heavy Metals (as Pb) | ≤8 ppm |
JPC 1997 - Arsenic (As) | ≤1.6 ppm |
JPC 1997 - Loss on Drying | ≤0.5 % |
JPC 1997 - Residue on Ignition | ≤0.10 % |
Assay (C₄H₁₁NO₃) (dried basis) | ≥99.9 % |
Absorbance of a 1M Solution - 260 nm | ≤0.06 |
Absorbance of a 1M Solution - 280 nm | ≤0.06 |
Absorbance of a 1M Solution - 400 nm | ≤0.01 |
Endotoxin Concentration (EU/g) | ≤2.5 |
Iron (Fe) | ≤1 ppm |
Lead (Pb) | ≤1 ppm |
Ultrapure Bioreagent Specifications | |
No Class 1,2,3 or other solvents are used or produced in the | |
manufacturing or purification of the product. | |
Manufactured exclusively for Avantor Performance Materials, LLC., by BioSpectra, Inc., Stroudsburg, PA | |
Elemental Impurities (USP 232, EP 5.20) - Information on elemental | |
impurities for this product is available on the associated Product | |
Regulatory Data Sheet and elemental impurity profile report. |
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