Sodium dihydrogen phosphate dihydrate, EMPROVE® ESSENTIAL Ph. Eur., BP, USP, JPE, E339, SAFC®

Supplier: EMD MILLIPORE – PCS CA EXCEP

Synonyms: Sodium phosphate monobasic dihydrateSodium dihydrogen orthophosphate dihydratePhosphoric acid (sodium hydrate)

1.06345.9011 1.06345.1000 1.06345.9026 1.06345.9026 1.06345.5000
CA1.06345.9026EA 1853.64 CAD
EM1.06345.9026 CA1.06345.9026 EM1.06345.1000 CA1.06345.5000 EM1.06345.9011
Sodium dihydrogen phosphate dihydrate, EMPROVE® ESSENTIAL Ph. Eur., BP, USP, JPE, E339, SAFC®
Sodium dihydrogen phosphate dihydrate

Hygroscopic.


  • Corresponds to Ph. Eur., BP, USP, JPE, E 339
  • Conforms to the purity criteria on food additives according to the current European Commission Regulation.


Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).

Formula: NaH₂PO₄·2H₂O
MW: 156.01 g/mol
Melting Pt: 60 °C
Density: 1.915 g/cm3 (20 °C)
MDL Number: MFCD00149209
CAS Number: 13472-35-0
EINECS: 231-449-2

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Specification Test Results

Assay (alkalimetric, calculated on dried substance) 98.0 - 100.5 %
Assay (alkalimetric; dried substance) 98.0 - 101.0 %
Identity passes test
Appearance of solution passes test
In water insoluble matter (calculated on dried substance) ≤ 0.15 %
pH-value (1 %, water) 4.1 - 4.7
pH-value (5 %; water) 4.2 - 4.5
pH-value (5.7 %; water) 4.1 - 4.5
Chloride (Cl) ≤ 0.005 %
Fluoride (F) ≤ 0.001 %
Hydrogenphosphate (HPO₄) ≤ 0.5 %
Sulfate (SO₄) ≤ 0.01 %
Heavy metals (as Pb) ≤ 0.0005 %
Al, Ca and other elements detectable with ammonia passes test
As (Arsenic) ≤ 0.0001 %
Cd (Cadmium) ≤ 0.0001 %
Fe (Iron) ≤ 0.001 %
Hg (Mercury) ≤ 0.0001 %
Pb (Lead) ≤ 0.0001 %
Substances reducing potassium permanganate (as O) passes test
Residual solvents (ICH Q3C) excluded by production process
Loss on drying (130 °C) 22.0 - 24.0 %

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