Polyethylene glycol 400, EMPROVE® ESSENTIAL Ph. Eur., SAFC®

Supplier: EMD MILLIPORE – PCS CA EXCEP

Synonyms: PEG 400

8.17003.5000 8.17003.5000

CA8.17003.5000EA 1131.58 CAD

CA8.17003.5000 EM8.17003.5000

Polyethylene glycol 400, EMPROVE® ESSENTIAL Ph. Eur., SAFC®

Polyethylene glycol 400

Clear, viscous, almost colorless liquid. Hygroscopic. For pharmaceutical production.

Formula: H(OCH₂CH₂)_nOH
MW: 400 g/mol
Boiling Pt: ∼250 °C (1013 hPa)
Melting Pt: 4…8 °C
Density: 1.13 g/cm³ (20 °C)
Flash Pt: 245 °C

MDL Number: MFCD00081839
CAS Number: 25322-68-3

Specification Test Results

Acidity or alkalinity	Passes test
Appearance	Clear, viscous almost colorless hygroscopic
Appearance of solution	Passes test
Average Molecular Mass	380-420
Density (d20/20)	About 1.120
Dioxane (GC)	10ppm max
Ethylene glycol and diethylene glycol	0.4% max
Ethylene glycole (acc. to ICH-guideline class 2)	620ppm max
Ethylene Oxide (GC)	1ppm max
Formaldehyde (HCHO)	30ppm max
Heavy metals	20ppm max
Hydroxyl value	264-300
Identity	Passes test
Other Residual Solvents acc. to ICH guideline	excluded by the manufacturing process
Reducing substances	Passes test
Sulfated ash	0.2% max
Viscosity (20°C)	100-111mm²/s
Viscosity (20°C)	112-124mPa·s
Water	2.0% max

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