HIV-1 Trimeric GP140 protein-clade C, 16055 strain

Supplier: ReVacc Scientific

HIV-1 Trimeric GP140 protein-clade C, 16055 strain

HIV-1 Trimeric GP140 protein-clade C, 16055 strain

HIV-1 Trimeric GP140 protein-clade C, 16055 strain

HIV-1 Trimeric GP140 protein-clade C, 16055 strain

HIV-1 Trimeric GP140 protein-clade C, 16055 strain

HIV-1 Trimeric GP140 protein-clade C, 16055 strain

E7P43-100UG E7P43-500UG

77394-684EA 1168.41 CAD

77394-684 77394-686

HIV-1 Trimeric GP140 protein-clade C, 16055 strain

Proteins and Peptides

A recombinant trimeric form of the HIV-1 glycoprotein (GP protein) from 16055 strain (clade C, GenBank: ABL67444.1) was produced by human embryonic kidney HEK293 cells, followed by Lectin purification. This product contains ectodomain of GP protein (end at D664) with furin cleavage site replaced by a linker, a I559P mutation for stable trimer formation, and C-terminal 8 hexa-histidine tag. This product has been evaluated by Size Exclusion Chromatography (SEC) to confirm the trimer formation, SDS-PAGE gel for purity and ELISAs for binding, see results. A rabbit antibody 11B that targets 241 glycan hole (BG505 specific, catalog U90R79) does not to bind to this protein (ref: Cell Rep. 2016;16(9):2327-38.).

This product has been evaluated by Size Exclusion Chromatography (SEC) to confirm the trimer formation, SDS-PAGE gel for purity and ELISAs for binding, see results. A rabbit antibody 11B that targets 241 glycan hole (BG505 specific, catalog U90R79) does not to bind to this protein (ref: Cell Rep. 2016;16(9):2327-38.).

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