Anti-VHH Rabbit Monoclonal Antibody (PE (Phycoerythrin)) [clone: 45H8]

Supplier: Genscript

GenScript®

A02171-200

77007-632EA 393.7 CAD

77007-632

Anti-VHH Rabbit Monoclonal Antibody (PE (Phycoerythrin)) [clone: 45H8]

Antibodies

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

MonoRab™ technology guarantees high affinity: Kd ~10 to 11 M
No cross reactivity with other species
Specific to camelid IgG2 and IgG3
Recognize conformational epitopes of the VHH domain
Recognize both camelid and humanized VHHs

GenScript has developed a series of rabbit monoclonal (MonoRab) anti-VHH antibodies to facilitate your research of VHHs. Our anti-VHH antibodies recognize conformational epitopes of the VHH domain of camelid lgG2 and lgG3 subclasses. It is not necessary to add a tag to VHH for detection anymore.

Type:
Antigen: VHH
Clonality: Monoclonal
Clone: 45H8
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity:

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