DMP (Dimethyl pimelimidate dihydrochloride), Pierce™
Supplier: Thermo Scientific
Synonyms:
DMP, Pimelimidic acid dimethyl ester dihydrochloride, Dimethyl pimelimidate dihydrochloride, Dimethyl pimelinediimidate dihydrochloride, Dimethyl heptanebis(imidate) dihydrochloride
21666
21667
CAPI21666EA
173.15
CAD
CAPI21666
CAPI21667
DMP (Dimethyl pimelimidate dihydrochloride), Pierce™
DMP (Dimethyl pimelimidate dihydrochloride)
Thermo Scientific Pierce DMP is dimethyl pimelimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of a 7-atom spacer arm.
- Reactive groups: imidoester (both ends)
- Reactive towards: amino groups (primary amines)
- Mid-length reagent of three similar imidoester crosslinkers, which include DMA, DMP and DMS
- Water-soluble
- Imidoesters react with amines at alkaline pH values (pH 8-10) to form amidine bond
- Amidine bond retains net charge character of protein primary amine to which it reacts
- Reversible at high pH values
- Tool for study of quarternary structure of proteins
Caution: For Research Use Only. Not for use in diagnostic procedures.
Formula:
C₉H₁₈N₂O₂ MW: 259.17 g/mol Storage Temperature: Refrigerator |
MDL Number:
MFCD00038942 CAS Number: 58537-94-3 |
Specification Test Results
Product Line | Pierce™ |
Labeling Method | Chemical Labeling |
Crosslinker Type | Homobifunctional |
Reactive Moiety | Imidoester |
Spacer | Short |
Form | Powder |
Quantity | 50 mg |
Type | Crosslinker |
Solubility | Water |
Spacer Arm | 9.2 Å |
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