Human Recombinant IL-31 (Animal free) (from E. coli)

Supplier: FUJIFILM IRVINE SCIENTIFIC, INC

100-204AF-5UG 100-204AF-25UG 100-204AF-1MG 100-204AF-100UG 100-204AF-500UG
76293-950EA 113.92 CAD
76293-950 76294-000 76294-002 76294-004 76294-006 77660-740 77660-742
Human Recombinant IL-31 (Animal free) (from E. coli)
Proteins and Peptides

Tumor growth factor alpha (TGF-α) is a member of the epidermal growth factor (EGF) family. TGF-α function is mediated through binding the EGF receptor (EGFR) to activate receptor tyrosine kinase signaling. TGF-α functions as a mitogen to activate epithelial cell proliferation, growth, and differentiation.


  • High quality
  • Low endotoxin
  • Affordable


In the gastric mucosa, TGF-α production inhibits gastric acid secretion and therefore plays a central role in the pathogenesis of the stomach syndrome Ménétrier's disease. TGF-α is also produced in adult macrophages, brain cells, keratinocytes, and is widely expressed in cancer cells.


Caution: For research use only.

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SPECIFICATIONS

Protein/peptide name IL-31 (AF) IL-31 (AF) IL-31 (AF)
Environmentally Preferable
Protein synonyms IL-31|Interleukin-31 IL-31|Interleukin-31 IL-31|Interleukin-31
Protein/peptide type Recombinant Recombinant Recombinant
Protein Function Cytokine Cytokine Cytokine
Species Human Human Human
Source E. coli E. coli E. coli
Conjugation Unconjugated Unconjugated Unconjugated
Sequence SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T
Protease-free N N N
Animal-free Y Y Y
Nuclease-free N N N
Carrier-free Y Y Y
Endotoxin-free N N N
Endotoxin level Low Low Low
Endotoxin content Endotoxin LAL (EU/µg) ≤0.1 Endotoxin LAL (EU/µg) ≤0.1 Endotoxin LAL (EU/µg) ≤0.1
Accession no. Q6EBC2 Q6EBC2 Q6EBC2
Biological activity Bioactivity assay: STAT3 Activation in U-87 MG cells, ED50 ≤Detectable at ≤25 ng/ml, bioactivity ≥0 Bioactivity assay: STAT3 Activation in U-87 MG cells, ED50 ≤Detectable at ≤25 ng/ml, bioactivity ≥0 Bioactivity assay: STAT3 Activation in U-87 MG cells, ED50 ≤Detectable at ≤25 ng/ml, bioactivity ≥0
Purity ≥95% ≥95% ≥95%
Grade RUO RUO
Formulation 20 mM sodium phosphate, 50 mM sodium chloride, pH 7.5 20 mM sodium phosphate, 50 mM sodium chloride, pH 7.5 20 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Molecular weight 15.8 kDa, monomer 15.8 kDa, monomer 15.8 kDa, monomer
Reconstitution instructions Sterile water at 0.1 mg/ml Sterile water at 0.1 mg/ml Sterile water at 0.1 mg/ml
Storage conditions −20 °C −20 °C −20 °C
Shipping temperature RT RT RT
Tested applications Bioassay Bioassay Bioassay

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