Mouse Recombinant VCAM-1 (from CHO cells)

Supplier: Peprotech

315-37-10UG 315-37-50UG 315-37-100UG 315-37-250UG 315-37-500UG 315-37-1MG
76303-962EA 196.27 CAD
76303-962 76303-964 76303-966 76304-088 76304-090 76304-092
Mouse Recombinant VCAM-1 (from CHO cells)
Proteins and Peptides

VCAM is a 110 kDa, cell surface integral membrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. The primary function of VCAM-1 is the mediation of leukocyte endothelial cell adhesion and signal transduction. VCAM-1 may play a vital role in the development of several diseases, including atherosclerosis and rheumatoid arthritis. The human VCAM-1 gene codes for a 715 amino acid transmembrane glycoprotein containing a 19 amino acid cytoplasmic domain, a 22 amino acid transmembrane domain, and a 674 amino acid extracellular domain. Recombinant Murine VCAM-1 is a 74.4 kDa glycoprotein comprising the extracellular domain (674 amino acid residues) of VCAM-1. Monomeric glycosylated VCAM-1 migrates at an apparent molecular weight of approximately 87-97 kDa by SDS-PAGE analysis under reducing conditions.

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