Mouse JAM-A - F11R ELISA Kit, Rockland Immunochemicals

Supplier: Rockland Immunochemicals

KOA0721

76235-922EA 976.44 CAD

76235-922

Mouse JAM-A - F11R ELISA Kit, Rockland Immunochemicals

Assays ELISAs

Mouse JAM-A - F11R AccuSignal ELISA Kit

Natural and recombinant mouse JAM-A.
There is no detectable cross-reactivity with other relevant proteins.
Expression system for standard: NSO; Immunogen sequence: K27-G238

Junctional adhesion molecule A(JAM-A) is a protein that in humans is encoded by the F11R gene. It is mapped to 1q23.3. This gene is an immunoglobulin-like molecule that colocalizes with tight junctions in endothelium and epithelium and is also found on blood leukocytes and platelets. JAM-A plays an important role in the regulation of tight junction assembly in epithelia. In addition, it can act as a receptor for reovirus, a ligand for the integrin LFA1, involved in leukocyte transmigration, and a platelet receptor. JAM-A has a nonredundant role in controlling DC motility, trafficking to lymph nodes, and activation of specific immunity.

Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1ml per well of the 2000pg/ml, 1000pg/ml, 500pg/ml, 250pg/ml, 125pg/ml, 62.5pg/ml, 31.2pg/ml mouse JAM-A standard solutions into the precoated 96-well plate. Add 0.1ml of the sample diluent buffer into the control well (Zero well). Add 0.1ml of each properly diluted sample of mouse cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each mouse JAM-A standard solution and each sample be measured in duplicate.

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