IPTG (isopropyl-β-D-thiogalactopyranoside) ≥98% (by HPLC on dried basis), Biotech Reagent, cGMP-manufactured, J.T.Baker®
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
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Warning
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Synonyms:
(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol
, IPTG
, Isopropyl Beta-D-1-thiogalactopyranoside
Management of Change (MOC) category = R
Reduce risk in your bioprocessing applications with Avantor J.T.Baker brand cGMP manufactured IPTG.
- cGMP manufactured under ICHQ7
- High-purity (>98% by HPLC)
- Low microbial, trace metals and endotoxin content
- Consistent lot-to-lot protein induction performance
- TSE/BSE-free
- 1,4-Dioxane-free
J.T Baker brand cGMP manufactured IPTG is performance tested to assure consistent lot-to-lot biological induction, and processed to remove and control product/process related impurities, with minimal lot-to-lot variability for improved protein expression.
Fully validated and documented through Batch Process Records (BPR) including analytical test data, stability protocol and impurity profile.
Packaging: Packaged in moisture permeation resistant controlled packaging.
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Formula:
C₉H₁₈O₅S MW: 238.31 g/mol Melting Pt: 110…122 °C |
MDL Number:
MFCD00063273 CAS Number: 367-93-1 |
Specification Test Results
| GMP Manufactured Product | |
| Store and ship product between 2 and 8 °C | |
| CAUTION: For Manufacturing, processing or repackaging | |
| Appearance (white to off-white solid) | Passes Test |
| Identification (IR) | Passes Test |
| pH of 5% Solution | 5.00 - 7.00 |
| Specific Rotation @ 25 °C | -34.5 - -28.5 Degree |
| Melting Point | 110 - 122 °C |
| Water (H₂O), For Information Only | |
| Purity (by HPLC) (anhydrous basis) | ≥98 % |
| Assay (by HPLC) (anhydrous basis) | 98 - 102 |
| Endotoxin Concentration, EU/g | |
| Residual Methanol | ≤3000 ppm |
| Residual Ethanol | ≤5000 ppm |
| Residual Isopropanol | ≤5000 ppm |
| Residual Ethyl Acetate | ≤5000 ppm |
| Total Aerobic Microbial Count | ≤100 cfu/g |
| Total Yeast and Mold Count | ≤100 cfu/g |
| Biological Induction Characterization (induction response @ 1mM) | |
| Arsenic (As), For Information Only | |
| Cadmium (Cd), For Information Only | |
| Mercury (Hg), For Information Only | |
| Lead (Pb), For Information Only | |
| Cobalt (Co), For Information Only | |
| Nickel (Ni), For Information Only | |
| Vanadium (V), For Information Only | |
| Silver (Ag), For Information Only | |
| Gold (Au), For Information Only | |
| Iridium (Ir), For Information Only | |
| Osmium (Os), For Information Only | |
| Palladium (Pd), For Information Only | |
| Platinum (Pt), For Information Only | |
| Rhodium (Rh), For Information Only | |
| Ruthenium (Ru), For Information Only | |
| Selenium (Se), For Information Only | |
| Thallium (Tl), For Information Only | |
| Barium (Ba), For Information Only | |
| Chromium (Cr), For Information Only | |
| Copper (Cu), For Information Only | |
| Lithium (Li), For Information Only | |
| Molybdenum (Mo), For Information Only | |
| Antimony (Sb), For Information Only | |
| Tin (Sn), For Information Only | |
| Aluminum (Al), For Information Only | |
| Iron (Fe), For Information Only | |
| Manganese (Mn), For Information Only | |
| Zinc (Zn), For Information Only | |
| Residual Solvents: The Class 3 solvents Ethanol, Isopropanol, Ethyl | |
| Acetate and the Class 2 solvent Methanol are likely to be present. These solvents are quantified and reported on each batch. No other | |
| Class 1,2,3, or other solvents are used or produced in the production | |
| process. Dioxane was not used in the manufacturing process. | |
| Bacterial Induction characterization: Test performed at 1 mM of IPTG (E. | |
| Coli. protein expression) | |
| IPTG is highly hygroscopic. Allow packaging/container to equilibrate to | |
| room temperature before opening for analysis. Ensure sample is kept dry | |
| (such as in a desiccator) after opening. |
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