Mouse Recombinant R-Spondin-1 (from CHO cells)

Supplier: Peprotech

315-32-5UG 315-32-20UG 315-32-100UG 315-32-250UG 315-32-500UG 315-32-1MG

75999-408EA 214.5 CAD

75999-408 75999-410 75999-412 75999-414 75999-416 75999-418

Mouse Recombinant R-Spondin-1 (from CHO cells)

Proteins and Peptides

R-Spondin-1 (Rspo-1) belongs to the (Rspo) family of Wnt modulators. Currently, the family consists of four structurally related secreted ligands (Rspo 1-4), all containing the furin-like and thrombospondin structural domains. Rspo-1 is expressed in certain areas of the developing central nervous system, as well as in the adrenal glands, ovary, testis, thyroid, and trachea. Rspo can interact with the Frizzled/LRP6 receptor complex in a manner that stimulates the Wnt/beta-catenin signaling pathway. Recombinant Murine R-Spondin-1 is a 27.1 kDa protein consisting of 245 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0 kDa by SDS-PAGE analysis under reducing conditions.

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