Mouse Recombinant LIF (from E. coli)

Supplier: Peprotech

250-02-5UG 250-02-25UG 250-02-100UG 250-02-250UG 250-02-500UG 250-02-1MG

75999-522EA 209.84 CAD

75999-522 75999-524 75999-526 75999-528 75999-530 75999-532

Mouse Recombinant LIF (from E. coli)

Proteins and Peptides

LIF is a pleiotrophic factor produced by multiple cell types, including T cells, myelomonocytic lineages, fibroblasts, liver, heart and melanoma. LIF promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Other activities include the stimulation of acute phase protein synthesis by hepatocytes, stimulation of differentiation of cholinergic nerves, and suppression of adipogenesis by inhibiting the lipoprotein lipase in adipocytes. While human LIF is active on mouse cells and is widely used in the maintenance of murine ESC to prevent spontaneous differentiation, mouse LIF is not active on human cells due to its inability to bind to the human LIF receptor. Recombinant Murine LIF is a 19.9 kDa protein containing 180 amino acids residues, including three disulfide bonds.

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