Human;Mouse;Rat Recombinant Activin A (from CHO cells)

Supplier: Peprotech

120-14P-2UG 120-14P-10UG 120-14P-50UG 120-14P-100UG 120-14P-250UG 120-14P-500UG 120-14P-1MG
75999-424EA 214.5 CAD
75999-424 75999-426 75999-428 75999-430 75999-432 75999-434 75999-436
Human;Mouse;Rat Recombinant Activin A (from CHO cells)
Proteins and Peptides

Activin A is a TGF-β family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Activin A binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). Activins are homodimers or heterodimers of different β subunits. They are produced as precursor proteins with an amino terminal propeptide that is cleaved to release the C-terminal bioactive ligand. Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.

Order Now


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR