Human Recombinant sIL-4Ra (from CHO Cells)

Supplier: Peprotech

200-04RC-5UG 200-04RC-20UG 200-04RC-100UG 200-04RC-250UG 200-04RC-500UG 200-04RC-1MG
75999-498EA 209.84 CAD
75999-498 75999-500 75999-502 75999-504 75999-506 75999-508
Human Recombinant sIL-4Ra (from CHO Cells)
Proteins and Peptides

IL-4 can signal through type I and type II receptor complexes, which share a common gamma chain (γc). The type I receptor contains, in addition to the γc, an IL-4Rα subunit, whereas the type II receptor contains the IL-13Rα. The secreted extracellular domain of IL-4Rα, called sIL-4Rα, binds IL-4 and antagonizes its activity. It plays an important role in regulating the differentiation of naïve CD4+ T cells and class switching to IgG1 and IgE. PeproTech's

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