Human Recombinant HGF (from HEK293 cells)

Supplier: Peprotech

100-39H-5UG 100-39H-25UG 100-39H-100UG 100-39H-250UG 100-39H-500UG 100-39H-1MG
75999-378EA 213.93 CAD
75999-378 75999-380 75999-382 75999-384 75999-386 75999-388
Human Recombinant HGF (from HEK293 cells)
Proteins and Peptides

HGF is a potent, mesenchymally-derived mitogen for mature parenchymal hepatocytes, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include the induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear, polypeptide-precursor glycoprotein containing 697 amino acid residues. Proteolytic processing of this precursor generates the biologically active heterodimeric form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held together by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 234 amino acid residues. Recombinant Human HGF, sourced from

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