6-keto Prostaglandin F1α ELISA Kit, Cayman Chemical Company
Supplier: Cayman Chemical Company
515211-480
515211-96
75816-880EA
2377.68
CAD
75816-880
75816-882
6-keto Prostaglandin F1α ELISA Kit, Cayman Chemical Company
Assays
ELISAs
For the quantification of 6-keto PGF1α in various samples.
- Detect 6-keto PGF1α, a surrogate for prostacyclin synthesis in multiple sample types
- Assay 24 samples in triplicate or 36 samples in duplicate
- Measure 6-keto PGF1α levels down to 6 pg/mL
- Incubation: 18 hours | Development: 90 – 120 minutes | Read: Colorimetric at 405 – 420 nm
Prostacyclin is formed from arachidonic acid primarily by the vascular endothelium and renal cortex. It is a potent vasodilator and inhibitor of platelet aggregation. PGI2 is non-enzymatically hydrated to 6-keto PGF1α (t½ = 2 – 3 minutes), and then quickly converted to the major metabolite, 2,3-dinor-6-keto PGF1α (t½ = 30 minutes).
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