Anti-CDKN1B Mouse Monoclonal Antibody (CF488A) [clone: SX53G8]

Supplier: Biotium

BNC881237-100 BNC881237-500

75967-204EA 325.12 CAD

75967-204 75967-206

Anti-CDKN1B Mouse Monoclonal Antibody (CF488A) [clone: SX53G8]

Antibodies

This antibody recognizes a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: CDKN1B
Clonality: Monoclonal
Clone: Clone SX53G8
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Human, Monkey, Mouse, Rat

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