Anti-EPX Mouse Monoclonal Antibody (Biotin) [clone: AHE-1]

Supplier: Biotium

BNCB1231-100 BNCB1231-500

75925-812EA 325.12 CAD

75925-812 75925-814

Anti-EPX Mouse Monoclonal Antibody (Biotin) [clone: AHE-1]

Antibodies

Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).

Type: Primary
Antigen: EPX
Clonality: Monoclonal
Clone: Clone AHE-1
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human

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