Anti-CGB Mouse Monoclonal Antibody (CF660R) [clone: HCGb/54 HCGb/459]

Supplier: Biotium

BNC611224-100 BNC611224-500

75951-828EA 325.12 CAD

75951-828 75951-830

Anti-CGB Mouse Monoclonal Antibody (CF660R) [clone: HCGb/54 HCGb/459]

Antibodies

This MAb reacts with a protein of 22 kDa, identified as β sub-unit of HCG. It does not cross react with the α sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The beta subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®660R is a far-red fluorescent dye (Ex/Em 663/682 nm) with superior brightness and unrivaled photostability among spectrally similar dyes.

Type: Primary
Antigen: CGB
Clonality: Monoclonal
Clone: Clone HCGb/54 HCGb/459
Conjugation: CF660R
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Human

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