Anti-CHGA Mouse Monoclonal Antibody (CF647) [clone: LK2H10 PHE5 CGA414]

Supplier: Biotium

BNC471223-100 BNC471223-500

75908-804EA 325.12 CAD

75908-804 75908-806

Anti-CHGA Mouse Monoclonal Antibody (CF647) [clone: LK2H10 PHE5 CGA414]

Antibodies

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: CHGA
Clonality: Monoclonal
Clone: Clone LK2H10 PHE5 CGA414
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human, Monkey, Mouse, Pig, Rat

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