Anti-CD74 Mouse Monoclonal Antibody (Biotin) [clone: LN-2 CLIP/813]

Supplier: Biotium

BNCB1207-100 BNCB1207-500

75910-646EA 325.12 CAD

75910-646 75910-648

Anti-CD74 Mouse Monoclonal Antibody (Biotin) [clone: LN-2 CLIP/813]

Antibodies

This antibody recognizes a protein of ~35 kDa, identified as CD74. It is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).

Type: Primary
Antigen: CD74
Clonality: Monoclonal
Clone: Clone LN-2 CLIP/813
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Human

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