Anti-CD74 Mouse Monoclonal Antibody (CF488A) [clone: LN-2 CLIP/813]

Supplier: Biotium

BNC881207-500 BNC881207-100

75907-428EA 900.17 CAD

75907-428 75910-658

Anti-CD74 Mouse Monoclonal Antibody (CF488A) [clone: LN-2 CLIP/813]

Antibodies

This antibody recognizes a protein of ~35 kDa, identified as CD74. It is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: CD74
Clonality: Monoclonal
Clone: Clone LN-2 CLIP/813
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Human

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