Anti-CD74 Mouse Monoclonal Antibody (CF640R) [clone: LN-2 CLIP/813]

Supplier: Biotium

BNC401207-100 BNC401207-500

75907-446EA 325.12 CAD

75907-446 75907-448

Anti-CD74 Mouse Monoclonal Antibody (CF640R) [clone: LN-2 CLIP/813]

Antibodies

This antibody recognizes a protein of ~35 kDa, identified as CD74. It is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Type: Primary
Antigen: CD74
Clonality: Monoclonal
Clone: Clone LN-2 CLIP/813
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Human

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