Anti-NEFH & NEFL Mouse Monoclonal Antibody (Biotin) [clone: RT-97 NR-4]

Supplier: Biotium

BNCB1201-100 BNCB1201-500

75968-532EA 325.12 CAD

75968-532 75968-534

Anti-NEFH & NEFL Mouse Monoclonal Antibody (Biotin) [clone: RT-97 NR-4]

Antibodies

This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Type: Primary
Antigen: NEFH & NEFL
Clonality: Monoclonal
Clone: Clone RT-97 NR-4
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Chicken, Human, Mouse, Pig, Rat

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