Anti-NEFH & NEFL Mouse Monoclonal Antibody (CF647) [clone: RT-97 NR-4]

Supplier: Biotium

BNC471201-100 BNC471201-500

75965-824EA 325.12 CAD

75965-824 75965-826

Anti-NEFH & NEFL Mouse Monoclonal Antibody (CF647) [clone: RT-97 NR-4]

Antibodies

This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: NEFH & NEFL
Clonality: Monoclonal
Clone: Clone RT-97 NR-4
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Chicken, Human, Mouse, Pig, Rat

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