Anti-Cytokeratin Mouse Monoclonal Antibody (CF594) [clone: KRTL/1077 KRTH/1076]

Supplier: Biotium

BNC941100-100 BNC941100-500
75909-938EA 325.12 CAD
75909-938 75909-940
Anti-Cytokeratin Mouse Monoclonal Antibody (CF594) [clone: KRTL/1077 KRTH/1076]
Antibodies
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRTL/KRTH is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: Not Applicable
Clonality: Monoclonal
Clone: Clone KRTL/1077 KRTH/1076
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Human, Rat
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