Anti-HLA-DRA Mouse Monoclonal Antibody (CF594) [clone: 19-26.1]

Supplier: Biotium

BNC941082-100 BNC941082-500

75961-150EA 325.12 CAD

75961-150 75961-152

Anti-HLA-DRA Mouse Monoclonal Antibody (CF594) [clone: 19-26.1]

Antibodies

This MAb reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: HLA-DRA
Clonality: Monoclonal
Clone: Clone 19-26.1
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human

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