Anti-VEGFA Mouse Monoclonal Antibody (CF488A) [clone: VEGF/1063]

Supplier: Biotium

BNC881063-100 BNC881063-500

75979-032EA 325.12 CAD

75979-032 75979-034

Anti-VEGFA Mouse Monoclonal Antibody (CF488A) [clone: VEGF/1063]

Antibodies

This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: VEGFA
Clonality: Monoclonal
Clone: Clone VEGF/1063
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Dog, Human, Mouse, Rabbit, Rat

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