Anti-CHGA Mouse Monoclonal Antibody (CF488A) [clone: CGA414 CGA/777 CGA/798]

Supplier: Biotium

BNC881060-100 BNC881060-500

75908-632EA 325.12 CAD

75908-632 75908-634

Anti-CHGA Mouse Monoclonal Antibody (CF488A) [clone: CGA414 CGA/777 CGA/798]

Antibodies

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: CHGA
Clonality: Monoclonal
Clone: CGA414 CGA/777 CGA/798
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human, Monkey, Mouse, Pig, Ra

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