Anti-TFRC Mouse Monoclonal Antibody (CF594) [clone: TFRC/1059]

Supplier: Biotium

BNC941059-100 BNC941059-500

75918-094EA 325.12 CAD

75918-094 75918-096

Anti-TFRC Mouse Monoclonal Antibody (CF594) [clone: TFRC/1059]

Antibodies

This antibody recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: TFRC
Clonality: Monoclonal
Clone: TFRC/1059
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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