Anti-CD2 Mouse Monoclonal Antibody (Biotin) [clone: HuLy-m1]

Supplier: Biotium

BNCB1053-100 BNCB1053-500

75890-214EA 325.12 CAD

75890-214 75890-216

Anti-CD2 Mouse Monoclonal Antibody (Biotin) [clone: HuLy-m1]

Antibodies

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Type: Primary
Antigen: CD2
Clonality: Monoclonal
Clone: HuLy-m1
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Cat, Human

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