Anti-CD2 Mouse Monoclonal Antibody (CF405S) [clone: HuLy-m1]

Supplier: Biotium

BNC041053-100 BNC041053-500

75890-222EA 325.12 CAD

75890-222 75890-224

Anti-CD2 Mouse Monoclonal Antibody (CF405S) [clone: HuLy-m1]

Antibodies

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: CD2
Clonality: Monoclonal
Clone: HuLy-m1
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Cat, Human

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